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Tumor Expansion

MedGen UID:
275514
•Concept ID:
C1519678
•
Neoplastic Process

Definition

Growth of a tumor involving either an increase in size of a continuous tumor tissue mass or translocation of tumor cells to secondary sites. (NCI) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTumor Expansion

Professional guidelines

PubMed

Primary Aldosteronism: Spatial Multiomics Mapping of Genotype-Dependent Heterogeneity and Tumor Expansion of Aldosterone-Producing Adenomas.
Gong S, Sun N, Meyer LS, Tetti M, Koupourtidou C, Krebs S, Masserdotti G, Blum H, Rainey WE, Reincke M, Walch A, Williams TA
Hypertension 2023 Jul;80(7):1555-1567. Epub 2023 May 1 doi: 10.1161/HYPERTENSIONAHA.123.20921. PMID: 37125608Free PMC Article
Differential Diagnosis in Hypophysitis: First Report on a Spindle Cell Rhabdomyosarcoma of the Pituitary Gland.
Ahmeti H, Jüttner E, Röcken C, Jansen O, Laudes M, Synowitz M
J Neurol Surg A Cent Eur Neurosurg 2023 May;84(3):295-299. Epub 2021 Nov 15 doi: 10.1055/s-0041-1735857. PMID: 34781400
Diagnosis and treatment of jaw tumors in children.
Chuong R, Kaban LB
J Oral Maxillofac Surg 1985 May;43(5):323-32. doi: 10.1016/0278-2391(85)90251-4. PMID: 2985771

Recent clinical studies

Etiology

Vascular disrupting agents in cancer therapy.
Smolarczyk R, Czapla J, Jarosz-Biej M, Czerwinski K, Cichoń T
Eur J Pharmacol 2021 Jan 15;891:173692. Epub 2020 Oct 29 doi: 10.1016/j.ejphar.2020.173692. PMID: 33130277
Thyroid Disorders and Hemostasis.
Elbers LPB, Squizzato A, Gerdes VEA
Semin Thromb Hemost 2018 Oct;44(7):676-682. Epub 2018 Jul 25 doi: 10.1055/s-0038-1666825. PMID: 30045389
Mechanisms of HBV-induced hepatocellular carcinoma.
Levrero M, Zucman-Rossi J
J Hepatol 2016 Apr;64(1 Suppl):S84-S101. doi: 10.1016/j.jhep.2016.02.021. PMID: 27084040
Molecular mechanisms of HBV-associated hepatocarcinogenesis.
Guerrieri F, Belloni L, Pediconi N, Levrero M
Semin Liver Dis 2013 May;33(2):147-56. Epub 2013 Jun 8 doi: 10.1055/s-0033-1345721. PMID: 23749671
Hepatitis B virus-induced oncogenesis.
Lupberger J, Hildt E
World J Gastroenterol 2007 Jan 7;13(1):74-81. doi: 10.3748/wjg.v13.i1.74. PMID: 17206756Free PMC Article

Diagnosis

Glioblastoma disrupts cortical network activity at multiple spatial and temporal scales.
Meyer J, Yu K, Luna-Figueroa E, Deneen B, Noebels J
Nat Commun 2024 May 27;15(1):4503. doi: 10.1038/s41467-024-48757-5. PMID: 38802334Free PMC Article
ARID1 and BRG1 Expression in Endometrial Cancer.
Kontomanolis EN, Symeonidis P, Nikolettos K, Perros P, Rody A, Tsikouras P, Nikolettos N, Giatromanolaki A
In Vivo 2024 May-Jun;38(3):1260-1265. doi: 10.21873/invivo.13563. PMID: 38688602Free PMC Article
Molecular Imaging of Pituitary Tumors.
Gillett D, MacFarlane J, Bashari W, Crawford R, Harper I, Mendichovszky IA, Aloj L, Cheow H, Gurnell M
Semin Nucl Med 2023 Jul;53(4):530-538. Epub 2023 Mar 23 doi: 10.1053/j.semnuclmed.2023.02.005. PMID: 36966020
Hepatitis B virus-induced oncogenesis.
Lupberger J, Hildt E
World J Gastroenterol 2007 Jan 7;13(1):74-81. doi: 10.3748/wjg.v13.i1.74. PMID: 17206756Free PMC Article
Nitric oxide and angiogenesis.
Ziche M, Morbidelli L
J Neurooncol 2000 Oct-Nov;50(1-2):139-48. doi: 10.1023/a:1006431309841. PMID: 11245273

Therapy

Metabolic control of cancer metastasis: role of amino acids at secondary organ sites.
Karno B, Edwards DN, Chen J
Oncogene 2023 Nov;42(47):3447-3456. Epub 2023 Oct 18 doi: 10.1038/s41388-023-02868-3. PMID: 37848626Free PMC Article
Vascular disrupting agents in cancer therapy.
Smolarczyk R, Czapla J, Jarosz-Biej M, Czerwinski K, Cichoń T
Eur J Pharmacol 2021 Jan 15;891:173692. Epub 2020 Oct 29 doi: 10.1016/j.ejphar.2020.173692. PMID: 33130277
Role of the NLRP3 Inflammasome: Insights Into Cancer Hallmarks.
Lin TY, Tsai MC, Tu W, Yeh HC, Wang SC, Huang SP, Li CY
Front Immunol 2020;11:610492. Epub 2021 Feb 3 doi: 10.3389/fimmu.2020.610492. PMID: 33613533Free PMC Article
Anti-tumor activities of lipids and lipid analogues and their development as potential anticancer drugs.
Murray M, Hraiki A, Bebawy M, Pazderka C, Rawling T
Pharmacol Ther 2015 Jun;150:109-28. Epub 2015 Jan 17 doi: 10.1016/j.pharmthera.2015.01.008. PMID: 25603423
Prolactinomas and pregnancy.
Bronstein MD
Pituitary 2005;8(1):31-8. doi: 10.1007/s11102-005-5083-4. PMID: 16411066

Prognosis

ARID1 and BRG1 Expression in Endometrial Cancer.
Kontomanolis EN, Symeonidis P, Nikolettos K, Perros P, Rody A, Tsikouras P, Nikolettos N, Giatromanolaki A
In Vivo 2024 May-Jun;38(3):1260-1265. doi: 10.21873/invivo.13563. PMID: 38688602Free PMC Article
Clonal dominance defines metastatic dissemination in pancreatic cancer.
Ho IL, Li CY, Wang F, Zhao L, Liu J, Yen EY, Dyke CA, Shah R, Liu Z, Çetin AO, Chu Y, Citron F, Attanasio S, Corti D, Darbaniyan F, Del Poggetto E, Loponte S, Liu J, Soeung M, Chen Z, Jiang S, Jiang H, Inoue A, Gao S, Deem A, Feng N, Ying H, Kim M, Giuliani V, Genovese G, Zhang J, Futreal A, Maitra A, Heffernan T, Wang L, Do KA, Gargiulo G, Draetta G, Carugo A, Lin R, Viale A
Sci Adv 2024 Mar 15;10(11):eadd9342. Epub 2024 Mar 13 doi: 10.1126/sciadv.add9342. PMID: 38478609
Gastric Cancer Vascularization and the Contribution of Reactive Oxygen Species.
Biagioni A, Peri S, Versienti G, Fiorillo C, Becatti M, Magnelli L, Papucci L
Biomolecules 2023 May 25;13(6) doi: 10.3390/biom13060886. PMID: 37371466Free PMC Article
mTOR inhibition attenuates chemosensitivity through the induction of chemotherapy resistant persisters.
Liu Y, Azizian NG, Sullivan DK, Li Y
Nat Commun 2022 Nov 17;13(1):7047. doi: 10.1038/s41467-022-34890-6. PMID: 36396656Free PMC Article
Necrotic reshaping of the glioma microenvironment drives disease progression.
Markwell SM, Ross JL, Olson CL, Brat DJ
Acta Neuropathol 2022 Mar;143(3):291-310. Epub 2022 Jan 17 doi: 10.1007/s00401-021-02401-4. PMID: 35039931

Clinical prediction guides

Clonal dominance defines metastatic dissemination in pancreatic cancer.
Ho IL, Li CY, Wang F, Zhao L, Liu J, Yen EY, Dyke CA, Shah R, Liu Z, Çetin AO, Chu Y, Citron F, Attanasio S, Corti D, Darbaniyan F, Del Poggetto E, Loponte S, Liu J, Soeung M, Chen Z, Jiang S, Jiang H, Inoue A, Gao S, Deem A, Feng N, Ying H, Kim M, Giuliani V, Genovese G, Zhang J, Futreal A, Maitra A, Heffernan T, Wang L, Do KA, Gargiulo G, Draetta G, Carugo A, Lin R, Viale A
Sci Adv 2024 Mar 15;10(11):eadd9342. Epub 2024 Mar 13 doi: 10.1126/sciadv.add9342. PMID: 38478609
Metabolic control of cancer metastasis: role of amino acids at secondary organ sites.
Karno B, Edwards DN, Chen J
Oncogene 2023 Nov;42(47):3447-3456. Epub 2023 Oct 18 doi: 10.1038/s41388-023-02868-3. PMID: 37848626Free PMC Article
mTOR inhibition attenuates chemosensitivity through the induction of chemotherapy resistant persisters.
Liu Y, Azizian NG, Sullivan DK, Li Y
Nat Commun 2022 Nov 17;13(1):7047. doi: 10.1038/s41467-022-34890-6. PMID: 36396656Free PMC Article
A human CD137×PD-L1 bispecific antibody promotes anti-tumor immunity via context-dependent T cell costimulation and checkpoint blockade.
Geuijen C, Tacken P, Wang LC, Klooster R, van Loo PF, Zhou J, Mondal A, Liu YB, Kramer A, Condamine T, Volgina A, Hendriks LJA, van der Maaden H, Rovers E, Engels S, Fransen F, den Blanken-Smit R, Zondag-van der Zande V, Basmeleh A, Bartelink W, Kulkarni A, Marissen W, Huang CY, Hall L, Harvey S, Kim S, Martinez M, O'Brien S, Moon E, Albelda S, Kanellopoulou C, Stewart S, Nastri H, Bakker ABH, Scherle P, Logtenberg T, Hollis G, de Kruif J, Huber R, Mayes PA, Throsby M
Nat Commun 2021 Jul 21;12(1):4445. doi: 10.1038/s41467-021-24767-5. PMID: 34290245Free PMC Article
Nitric oxide and angiogenesis.
Ziche M, Morbidelli L
J Neurooncol 2000 Oct-Nov;50(1-2):139-48. doi: 10.1023/a:1006431309841. PMID: 11245273

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